Onder andere met: Natalie Portman (Jacqueline 'Jackie' Kennedy), Peter Sarsgaard (Robert F. Kennedy), Billy Crudup (Journalist), John Hurt (Priester), Caspar Phillipson (John F. Kennedy), John Carrol Lynch (Lyndon B. Johnson), Beth Grant (Claudia 'Lady Bird' Johnson), Max Casella (Jack Valenti), Richard E. Grant (William Walton), Julie Judd (Ethel Kennedy), Brody & Aiden Weinberg (John F. junior), Barbara Foliot (Pat Kennedy), Albain Venzo (Peter Lawford), Roland Pidoux (Pablo Casals), Georgie Glen (Rose Kennedy), Emmanuel Herault (Robert McNamara)